Atypical Femur Fractures: 81 Individual Personal Histories
نویسندگان
چکیده
منابع مشابه
Atypical femur fractures: 81 individual personal histories.
CONTEXT An online voluntary association of individuals who had incurred one or more atypical femur fractures (AFFs) while taking bisphosphonates for prevention or treatment of osteoporosis provided an opportunity to collect long-term histories. SETTING Individuals from a nationwide general community completed an anonymous survey documenting their history. PARTICIPANTS Within a larger cadre,...
متن کاملBisphosphonates and Atypical Fractures of Femur
Bisphosphonates are the most widely prescribed medicines for the treatment of osteoporosis and have generally been regarded as well-tolerated and safe drugs. Since 2005, there have been numerous case reports about atypical fractures of the femur linked to long-term treatment of osteoporosis with bisphosphonates. Some attempts to characterize pathophysiology and epidemiology of these fractures h...
متن کاملWeekly Teriparatide for Delayed Unions of Atypical Subtrochanteric Femur Fractures
INTRODUCTION The occurrence of atypical femur fractures (AFFs) in patients on prolonged bisphosphonate treatment has been gaining medical attention, but the use of pharmacotherapy for these fractures has not been explored in detail. The authors describe a case of AFFs successfully treated with once-weekly administration of 56.5 μg teriparatide (TPTD). CASE PRESENTATION The patient was a 74-ye...
متن کاملBisphosphonates and atypical subtrochanteric fractures of the femur
OBJECTIVES Bisphosphonates are widely used as first-line treatment for primary and secondary prevention of fragility fractures. Whilst they have proved effective in this role, there is growing concern over their long-term use, with much evidence linking bisphosphonate-related suppression of bone remodelling to an increased risk of atypical subtrochanteric fractures of the femur (AFFs). The obje...
متن کاملAssociation between alendronate and atypical femur fractures: a meta-analysis
Alendronate (ALN) is a commonly used drug for the treatment of osteoporosis. Atypical femur fractures (AFFs) have been associated with long-term use of ALN and have recently become the subject of considerable attention as ALN use increases. This meta-analysis aimed to determine the relationship between ALN and AFF. The Embase, PubMed, and Cochrane library databases were searched for relevant st...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2012
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2012-2590